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It was developed by Novo Nordisk through deliberate modification of the native GLP-1(7-37) peptide to create a molecule suitable for once-daily dosing
A pen containing a months worth of doses of 0.5 milligrams could drop from around $223 to as low as $78
(PubMed) Berezhnoy G, Laske C, Trautwein C
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NHS prescribing guidelines emphasise that GLP-1 medicines should be initiated and monitored by healthcare professionals experienced in their use
Side effects that some people using semaglutide experience include: Gastrointestinal issues, such as nausea, vomiting, diarrhea, constipation, heartburn, burping and stomach pains Less often, the following more serious side effects can also occur: Fatigue Rash and itching Swelling of the legs and hands Vision changes Fainting or dizziness Allergic reactions Higher risk for pancreatitis (inflammation of the pancreas) Hypoglycemia (especially when combined with other diabetes medications) Possible risk of increased heart rate and thyroid tumors, including cancer (a warning required by the FDA) If you experience any of these symptoms, call your doctor right away and get emergency medical treatment if the symptoms become severe
